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Game-Changer or Gimmick? 5 Powerful Insights Comparing Wegovy vs Zepbound for Weight Loss

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If you’ve been Googling “Wegovy vs Zepbound” like your next health breakthrough depends on it—you’re not alone. These two FDA-approved weight loss medications are making serious waves. But which one actually works better? Let’s break it down with real clinical data, a dash of sass, and a whole lot of clarity.

1. The Science Behind the Shots

Both Wegovy (semaglutide) and Zepbound (tirzepatide) are injectable medications designed to help people with obesity or weight-related conditions shed pounds. But here’s the kicker: they work differently.

  • Wegovy targets one hormone: GLP-1.
  • Zepbound? It’s a double whammy—GLP-1 and GIP.

So what’s GLP-1, anyway?

GLP-1 stands for glucagon-like peptide-1, a hormone released by your gut in response to eating. It’s part of a group called incretins, which help regulate blood sugar. GLP-1 does a few amazing things:

  • It stimulates insulin secretion when your blood sugar rises.
  • It slows down gastric emptying, so you feel fuller longer.
  • It reduces appetite by acting on the brain’s satiety centers.
  • And it lowers glucagon levels, which helps prevent blood sugar spikes.

In short, GLP-1 helps your body manage food intake and blood sugar like a boss. That’s why GLP-1 receptor agonists like Wegovy have become game-changers in the treatment of obesity and type 2 diabetes.

Now let’s talk about GIP.

GIP stands for glucose-dependent insulinotropic polypeptide. Like GLP-1, it’s an incretin hormone released after eating. Its main job? Stimulating insulin secretion—especially after meals. But GIP may also:

  • Enhance fat metabolism and influence how fat is stored
  • Support bone formation
  • Regulate appetite and satiety, though this is still being studied

While GIP is less well-known than GLP-1, combining the two—as Zepbound does—may create a synergistic effect that boosts weight loss and metabolic benefits.That dual-action mechanism may be why Zepbound is pulling ahead in the latest head-to-head clinical trials.

2. The Clinical Showdown: SURMOUNT-5

In a randomized trial of 751 participants without diabetes, researchers compared the two drugs over 72 weeks. The results?

  • Zepbound users lost an average of 20.2% of body weight (about 50.3 lbs).
  • Wegovy users lost 13.7% (around 33.1 lbs).

That’s a 47% greater relative weight loss with Zepbound. And yes, that’s a big deal.

You can dive into the full study breakdown on Advisory.com.

3. Waistlines and Wellness

Beyond the scale, Zepbound also helped participants lose more inches around the waist—7.2 inches vs. Wegovy’s 5.1 inches. Plus, Zepbound showed greater improvements in systolic blood pressure and other cardiometabolic markers.

Translation? It’s not just about looking good—it’s about feeling better and living longer.

4. Side Effects: The Real Talk

Both medications come with similar side effects: nausea, constipation, diarrhea, and vomiting. But fewer people on Zepbound dropped out due to side effects (6.1%) compared to Wegovy (8%).

So while neither is a walk in the park, Zepbound might be a bit easier to stick with.

5. The Bottom Line: Is Zepbound the Winner?

Based on current clinical evidence, Zepbound appears to outperform Wegovy in weight loss and metabolic improvements. But, here’s a key footnote: the study was funded by Eli Lilly, the maker of Zepbound. While the results are undeniably impressive, it’s wise to keep in mind that more independent research could offer broader insights. Transparency matters—and in science, more data never hurts.

Final Thoughts

In the battle of Wegovy vs Zepbound, the data leans in favor of Zepbound. But remember: the best medication is the one that works for you. Consult your healthcare provider before making a switch. Your body, your journey, your rules.

And if you’re ready to take the next step toward your healthiest self? You’ve got this. 

Zepbound Shortage

Zepbound Shortage

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What is Zepbound and why patients love it?

Zepbound is a relatively new injectable medication gaining popularity for weight loss. Here’s why people are excited about it:

  • Impressive Results: Clinical trials showed promising weight loss, with some patients losing up to 52 pounds, rivaling weight loss surgery results.
  • Dual Action: Unlike some weight-loss drugs, Zepbound targets two hormones. This dual approach may lead to more significant appetite suppression and improved blood sugar control.
  • Reduced Calorie Intake: By mimicking satiety hormones, Zepbound can help people feel fuller for longer, potentially leading to a natural reduction in calorie intake.
  • Potential Health Benefits: Studies suggest weight loss with Zepbound may improve blood sugar control and reduce the risk of weight-related health problems like heart disease and type 2 diabetes.

Which Zepbound Strength are not easily available?

  • Zepbound 2.5mg Injection ✔
  • Zepbound 5mg Injection
  • Zepbound 7.5mg Injection
  • Zepbound 10mg Injection
  • Zepbound 12.5mg Injection
  • Zepbound 15mg Injection

Zepbound Shortage Reasons 

The main and foremost reason for weight-loss drug Zepbound shortage is that its facing a surge in demand. Eli Lilly, the manufacturer, underestimated the drug’s popularity and can’t keep up with prescriptions for both diabetes and weight management. While they’re working on expanding production, it won’t be enough to meet current needs until sometime next year of 2025 or more. Some common challenges for the manufacturer may include:

  1. Unprecedented Demand: There has been a significant surge in demand for weight loss drugs, driven by their proven effectiveness and broadening indications for use. This demand has outstripped current manufacturing capacities.

  2. Manufacturing Challenges: Producing weight loss medications like Zepbound which is an injectable drug, involves complex manufacturing processes. Challenges in scaling up these processes to meet demand can lead to shortages.

  3. Supply Chain Issues: Zepbound is supplied in different countries, may be under different trade names and this global supply chain demand can cause raw material shortages, logistics issues, or regulatory challenges. Al these factors will definitely contribute to the problem to United States patients. These issues can delay production and distribution, exacerbating shortages.

  4. Regulatory Delays: Approvals are always needed for expanding manufacturing facilities or changing manufacturing processes can be time-consuming. These regulations may delay responses to increased demand.

  5. Market Dynamics: The entry of new patients in weight loss market and diabetes can suddenly increase the demand, which may not be immediately meetable by existing supply capabilities.

  6. Quality Control and Safety Issues: Zepbound is a drug that needs refrigeration. Therefore ensuring the safety and efficacy of increased production batches, safely and timely redistributing the drug to various drug vendors and then to pharmacies  can also lead to delays if problems are identified during quality checks.

This leaves patients struggling to find their medication and potentially facing weight regain. Please read this news article from CNBC regarding Zepbound shortage

Possible Impact of Zepbound Shortage 

Zepbound shortage has significant impact, affecting various stakeholders from patients to healthcare systems in multiple ways:

  1. Patient Health and Treatment: Patients who rely on Zepbound for weight management and related health issues like type 2 diabetesmay experience setbacks in their treatment plans. The shortage could lead to interrupted treatment, which can cause regression in health gains, increased weight, or a rebound in related health issues.

  2. Increased Healthcare Burden: Interruptions in effective weight management treatments can lead to increased healthcare visits, more intensive medical interventions, and potentially higher healthcare costs in the long term. This is especially true for chronic conditions that are managed through steady medication, where disruptions can lead to complications.

  3. Patient Stress and Anxiety: The uncertainty about time and difficulty in obtaining necessary medication can cause significant stress and anxiety for patients. This emotional strain can be compounded by the potential health repercussions of not being able to maintain their treatment regimen.

  4. Pressure on Healthcare Providers: Healthcare providers are also impacted as they need to manage patient care under these constrained conditions. This might involve spending more time to help patients navigate the shortage by finding alternative pharmacies, adjusting prescriptions based on availability, changing dosages to available ones, or switching to other treatment options that are not as positively impactful on health. All these alternative options adds to their workload and can strain resources.

  5. Economic Impact on Pharmaceutical Companies: While shortages can initially seem to be a demand opportunity for pharmaceutical companies, they can also lead to reputational damage and loss of trust among consumers. Companies like Eli Lilly with Zepbound shortage might face pressure to quickly resolve supply issues to maintain their market position and consumer trust.

The shortage of Zepbound underscores the need for robust supply chain management, strategic foresight in production capacities, and effective communication between pharmaceutical companies, healthcare providers, and patients to mitigate the adverse effects on public health and economic performance.

Zepbound alternatives

Zepbound is a relatively new once-weekly injection medication that has shown promising results for weight loss. However, due to its popularity, there is currently a shortage of Zepbound. If you’re unable to find Zepbound, here are some alternative medications your doctor might be interested in recommending you:

  • Wegovy (semaglutide)

This is another GLP-1 receptor agonist similar to Zepbound, but it targets only one hormone. Wegovy is also FDA-approved for chronic weight management and has been shown to be effective for weight loss. However, Wegovy is also facing supply shortages especially their 0.25mg and 0.5mg which are considered beginners dosages.

  • Saxenda (liraglutide)

Saxenda is also one of the GLP-1 receptor agonist injection that has been FDA-approved for weight loss. It works by increasing satiety and reducing appetite, leading to decreased calorie intake.

  • Mounjaro (dulaglutide)

Mounjaro is a GLP-1 receptor agonist that is FDA-approved for type 2 diabetes, but it can also cause weight loss as a side effect. It’s also injected once weekly. This is a perfect alternative to Zepbound. However being one of the alternatives, Mounjaro is causing severe shortages and it is also produced by Eli Lilly.

  • Ozempic (semaglutide)

Ozempic is the same medication as Wegovy, but it’s FDA-approved for type 2 diabetes, not weight loss. However, like Mounjaro, it can cause weight loss as a side effect.

  • Contrave (naltrexone/bupropion)

Contrave is an oral combination pill that works by regulating appetite and reducing cravings. It is not an injection medication and is taken orally once or twice daily.

  • Qsymia (phentermine/topiramate)

Qsymia is another combination pill that works by increasing feelings of fullness and reducing cravings. It is also taken orally, once daily.

  • Orlistat (Xenical or Alli)

Orlistat works by blocking the absorption of some dietary fat. It is available over-the-counter (Alli) or by prescription (Xenical) and is taken with meals.

Frequently asked Questions and Answers

Is There a Zepbound Shortage?

Yes, there is currently a Zepbound shortage in the United States. The Food and Drug Administration (FDA) maintains a drug shortage database, which confirms limited availability for most Zepbound dosages. 

This shortage is due to high demand for the weight-loss drug, exceeding Eli Lilly’s production capacity. 

How long Zepbound shortage will last?

The current shortage of Zepbound is expected to last through at least 2024 and beyond, particularly affecting certain doses. Eli Lilly, the manufacturer of Zepbound, has indicated that the shortages are due to unprecedented demand and challenges in scaling up production to meet this demand. 

They are actively working to increase manufacturing capacity, which should gradually help alleviate the shortages throughout 2024 and beyond. Source

Can you drink on zepbound?

When taking Zepbound (tirzepatide), it’s generally recommended to be cautious with alcohol consumption. While there is no specific contraindication for drinking alcohol while on Zepbound, several considerations should be kept in mind:

  1. Blood Sugar Fluctuations: Alcohol can affect blood sugar levels, potentially leading to hypoglycemia (low blood sugar) when combined with Zepbound, which is designed to help manage weight partly by influencing insulin levels.

  2. Dehydration Risks: Zepbound may slow gastric emptying, which can intensify the dehydrating effects of alcohol. It’s crucial to stay hydrated if you choose to drink.

  3. Caloric Intake: Alcohol contains calories that might counteract your weight loss efforts on Zepbound. Additionally, alcohol can lower inhibitions, possibly leading to less disciplined eating habits.

  4. Potential for Increased Side Effects: Although direct interactions between Zepbound and alcohol have not been extensively studied, alcohol might exacerbate side effects such as gastrointestinal discomfort or dizziness.

Moderation is Key: If you decide to drink alcohol while taking Zepbound, it’s best to do so in moderation. Guidelines suggest limiting intake to one drink per day for women and two for men, and never on an empty stomach to avoid an increased risk of hypoglycemia.

Please discuss your alcohol consumption with your healthcare provider, particularly when taking medications like Zepbound, to ensure that your treatment plan is safe and effective.

Zepbound Side effects

Zepbound Side Effects

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Great! Let’s talk about Zepbound and its side effects profile in detail here. Zepbound, known generically as tirzepatide, is a medication primarily used for managing type 2 diabetes. It works by mimicking the effects of natural hormones to help control blood sugar levels.

What is Zepbound

Zepbound, known generically as tirzepatide, is a medication primarily approved by FDA on November 8, 2023 for weight management or weight loss. Zepbound in simple terms works by mimicking the effects of natural hormones to help loose weight and also control blood sugar levels.

Zepbound Common Side Effects

These symptoms are usually mild to moderate and tend to improve over time as your body adjusts to the medication.

Gastrointestinal Issues

Nausea & Vomiting

Zepbound (tirzepatide) causing nausea and vomiting is one of the most common side effects. This can be attributed to its mechanism of action, particularly how it interacts with the digestive system and appetite regulation.

When Zepbound stimulates GLP-1 receptors, it can slow gastric emptying, which means food stays in the stomach longer than usual. This slower movement of food can lead to feelings of fullness or discomfort, resulting in nausea.

Nausea is often more pronounced when starting the medication or increasing the dose. As the body adjusts to Zepbound, the severity of nausea typically decreases over time. Some people may have a heightened sensitivity to medications that affect the gastrointestinal system, making them more prone to experiencing nausea.

It’s worth noting that while nausea is a common side effect, it’s usually temporary and manageable.

Diarrhea or Constipation

Another most common side effects of Zepbound are diarrhea or constipation.  These can be attributed to its effects on the gastrointestinal system. These side effects are are related to how the medication influences digestion and the function of the gut.

While slowing down gastric emptying – the rate at which food moves from the stomach to the intestines, can lead to constipation. However, for some individuals, this alteration in digestive process might swing the other way, causing diarrhea.

Changes in Intestinal Motility: The drug’s impact on the gut’s motility (the movement of the intestines that helps process and move food) can vary, leading to either increased or decreased activity. This variation can result in different bowel patterns for different individuals, including both diarrhea and constipation.

Effect on Gut Flora: All medications that affect the gastrointestinal tract can potentially alter the gut flora (the balance of microorganisms in the intestines). Changes in gut flora can lead to symptoms like diarrhea or constipation, although this is a less understood aspect of the medication’s effects.

Individual Differences in Response: People’s bodies can react differently to the same medication, due to factors like individual gut sensitivity, dietary habits, and overall health. This variation can lead to different GI side effects, including diarrhea or constipation.

Dosage and Adjustment Period: When starting Zepbound or changing dosages, the body can take time to adjust, leading to temporary GI symptoms. Often, these symptoms can resolve or become less severe as the body adapts to the medication.

Injection Site Reactions:

Since Zepbound is administered as an injection, some people may experience reactions at the site of injection, such as redness, itching, or swelling.

Injection site reactions typically include redness, swelling, pain, or itching at the site where the medication is injected. These reactions are usually due to the body’s immune response to the injection, mechanical irritation from the needle, or a reaction to the medication’s formula.

They are generally localized and temporary, often resolving within a few days. Rotating injection sites, using proper injection techniques, and possibly applying a cold pack can help reduce these reactions.

Allow Zepbound injection to cool down and let it come to room temperature before injecting. Take out the shot and let it sit at room temperature (RT) for at least 15-30 minutes and then inject accordingly. Coming to room temperature before administering can help in reducing injection site reactions. This practice is often recommended for most injectable medications. 

  • Decreased Appetite and Weight Loss: While this can be a benefit for some patients, it’s important to manage it carefully to ensure nutritional needs are met.
  • Fatigue: Some people might feel unusually tired or fatigued when taking Mounjaro.
  • Dizziness and Headaches: These symptoms can sometimes occur, particularly if blood sugar levels fluctuate.
Zepbound weight loss Injection

Zepbound Powerful Weight Loss Medication

Leave a Comment / FDA Approvals, Weight Loss / By

Brand name: Zepbound

Generic name: Tirzepatide

FDA Approval Date: 11/08/2023

Zepbound Doses

Zepbound is available in six doses (2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg). The higher the dose, the higher the cost.

  • Zepbound 2.5 mg/0.5 ml Pen Inj
  • Zepbound 5 mg/0.5 ml Pen Inj
  • Zepbound 7.5 mg/0.5 ml Pen Inj
  • Zepbound 10 mg/0.5 ml Pen Inj
  • Zepbound 12.5 mg/0.5 ml Pen Inj
  • Zepbound 15 mg/0.5 ml Pen Inj

Get Zepbound prescription filled within 24 hours, once available.
No long lines and no more waiting.

Zepbound Price $25

Zepbound price with insurance will vary depending on prescription coverage. Zepbound insurance coverage is required to get benefits of $25 copay savings program. Pay as little as $25 for 1 month or 3 months prescription with the Zepbound Savings Card. (Conditions apply)

Transfer Prescription to Medrocs Pharmacy
Get Coupon Information

What is Zepbound

Zepbound is a self injectable prescription medicine that is available in 6 different dosages. Zepbound is approved by FDA on November 8, 2023 for adults with obesity, or with excess weight (with a BMI of 30 kg/m2 or greater), or those who are overweight (with a BMI of 27 kg/m2 or greater). Medication is indicated to used with a low calorie diet plan and increased physical activity. 

How does Zepbound Work?

It works by mimicking two naturally occurring hormones in the body: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones play a role in regulating blood sugar, appetite, and energy balance.

Here’s how Zepbound works in more detail:

  • GIP receptor agonism: GIP is a hormone that stimulates insulin secretion and increases fat storage. Zepbound activates GIP receptors, which helps to increase insulin secretion and reduce fat storage.
  • GLP-1 receptor agonism: GLP-1 is a hormone that slows gastric emptying, reduces appetite, and increases insulin secretion. Zepbound activates GLP-1 receptors, which helps to slow gastric emptying, reduce appetite, and increase insulin secretion.

By mimicking these two hormones, Zepbound helps to promote weight loss by:

  • Reducing appetite: Zepbound can help you feel full for longer, which can help you eat less.
  • Slowing gastric emptying: Medication slows down the movement of food from your stomach to your small intestine, which can also help you feel full for longer.
  • Increasing insulin secretion: It helps your body use insulin more efficiently, which can help to lower blood sugar levels.
Zepbound Weight loss Medication

Zepbound Side Effects

Here are some of the potential side effects of Zepbound:

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal pain
  • Upper respiratory tract infection
  • Fatigue
  • Headache

If you experience any of these side effects, talk to your doctor. In most cases, the side effects are mild and go away on their own.

Serious side effects of Zepbound

Severe stomach problems. Sometimes stomach problems have been reported in people using Zepbound.

Kidney problems (kidney failure).  Diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems. Patients are suggested to drink more fluids.

Gallbladder problems. Gallbladder problems have happened in some people who use Zepbound. Pain is reported in upper stomach (abdomen). Fever, yellowing of skin or eyes (jaundice), or clay-colored stools have also been noticed.

Inflammation of the pancreas (pancreatitis). Severe pain in your stomach area (abdomen) with or without vomiting has been reported. You may feel the pain from your abdomen to your back.

Serious allergic reactions.  Serious allergic reaction, including swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting or feeling dizzy,  or very rapid heartbeat are also reported.

Low blood sugar (hypoglycemia). Zepbound with medicines that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, mood changes, hunger, weakness or feeling jittery.

Changes in vision in patients with type 2 diabetes. Changes in vision during treatment with Zepbound is noticed with some patients.

Depression or thoughts of suicide. Pay close attention to changes in your mood, behaviors, feelings or thoughts. Call your healthcare provider right away if you have any mental changes that are new, worse, or worry you.

Zepbound Savings Card

Zepbound Savings Card is a co-pay assistance program that can help eligible patients with commercial insurance save money on their Zepbound prescription. With the savings card, eligible patients may pay as little as $25 for a 1-month or 3-month prescription fill of Zepbound.

Eligibility Requirements

To be eligible for the Zepbound Savings Card, you must:

  • Have commercial drug insurance that covers Zepbound™(tirzepatide)
  • Have a prescription consistent with FDA-approved product labeling
  • Not be a governmental beneficiary (e.g., Medicare, Medicaid, TriCare)

Zepbound Coupon

Using Zepbound coupon, eligible patients may save up to $150 per 1-month prescription fill, $300 per 2-month prescription fill, or $450 per 3-month prescription fill. The maximum annual savings is $1,800 per calendar year.

How to Use the Savings Card or Coupon

To use the Zepbound Savings Card, you will need to present the card to your pharmacist at the time of your prescription drop-off or pickup. The pharmacist will apply the savings to your prescription and you will pay the reduced co-pay.

Activate Zepbound Coupon Here

Zepbound Cost

The list price for Zepbound (tirzepatide) is $1,059.87 per month. Actual cost for patients will vary depending on insurance coverage, pharmacy benefits and drug availability.

Patients with commercial insurance and covered: Patients with commercial insurance may be eligible for coverage of Zepbound. If they have coverage, they may still have to pay a co-pay, which can vary depending on their insurance plan. With the Zepbound Savings Card, eligible patients with commercial insurance may pay as little as $25 for a 1-month or 3-month prescription fill of Zepbound.

Patients with commercial insurance but not-covered: Patients with commercial insurance but no coverage may be eligible to obtain savings of up to $563 off your 1-month prescription fill of Zepbound. Month is defined as 28-days and up to 4 pens. Card savings are subject to a maximum monthly savings of up to $563 and a separate maximum annual savings of up to $7,319 per calendar year. Card may be used for a maximum of up to 13 prescription fills per calendar year.

As of today patients with commercial insurance but not-covered are paying $550 for a 4-week prescription after using zepbound coupon. Source

Patients without commercial insurance: Patients without commercial insurance may be eligible for financial assistance from Eli Lilly and Company, the manufacturer of Zepbound. The Eli Lilly Patient Support Program provides financial assistance to eligible patients who are unable to afford their medications.

Medicare and Medicaid coverage: Medicare and Medicaid do not currently cover Zepbound.

Here are some additional factors that can affect the cost of Zepbound:

  • Pharmacy: The cost of Zepbound can vary depending on the pharmacy where you fill your prescription. It is always a good idea to shop around to find the best price.
  • Discounts: There may be other discounts available for Zepbound, such as manufacturer rebates or coupons. You can check with your doctor or pharmacist to see if you are eligible for any discounts.

Zepbound vs Ozempic

Zepbound (tirzepatide) and Ozempic (semaglutide) are both glucagon-like peptide-1 (GLP-1) receptor agonists that are used to treat type 2 diabetes and promote weight loss. However, there are some key differences between the two medications.

Mechanism of action

  • Zepbound: Zepbound mimics two naturally occurring hormones in the body: GLP-1 and glucose-dependent insulinotropic polypeptide (GIP). GLP-1 slows gastric emptying, reduces appetite, and increases insulin secretion. GIP stimulates insulin secretion and increases fat storage. Zepbound activates both GLP-1 and GIP receptors, which helps to promote weight loss.

  • Ozempic: Ozempic mimics GLP-1, but it does not mimic GIP. This means that Ozempic may not be as effective at promoting weight loss as Zepbound.

Dosage and administration

  • Zepbound: Zepbound is available in six doses (2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, 15mg) and is injected once a week.

  • Ozempic: Ozempic is available in four doses (0.25mg, 0.5mg, 1mg and 2mg) and is injected once a week.

Weight loss efficacy

  • Zepbound: In clinical trials, Zepbound has been shown to be more effective at promoting weight loss than Ozempic. In one study, people taking Zepbound lost an average of 22.5% of their body weight after 68 weeks of treatment, while people taking Ozempic lost an average of 13.4% of their body weight.

  • Ozempic: Ozempic is still a very effective weight loss medication. In clinical trials, people taking Ozempic have lost an average of 10-15% of their body weight.

Side effects

  • Zepbound: The most common side effects of Zepbound are nausea, vomiting, diarrhea, constipation, abdominal pain, upper respiratory tract infection, fatigue, and headache.

  • Ozempic: The most common side effects of Ozempic are nausea, vomiting, diarrhea, constipation, abdominal pain, upper respiratory tract infection, fatigue, and headache.

Overall, Zepbound appears to be a more effective weight loss medication than Ozempic. However, Ozempic is still a very effective medication and may be a good option for people who cannot tolerate the side effects of Zepbound.

Zepbound Weight loss

Zepbound Weight Loss Results

In a clinical trial, Zepbound showed significant weight loss results over 72 weeks. Participants taking 5 mg of Zepbound weekly lost an average of 35.5 pounds (16.1 kg), those on 10 mg lost around 48.9 pounds (22 kg), and the 15 mg group saw an average weight loss of 52 pounds (23.6 kg).

These results were notably higher than the placebo group, which experienced an average weight loss of about 5.3 pounds (2.4 kg).

It’s important to note that individual results can vary, and these figures are averages from the study participants.

Source: https://www.drugs.com/medical-answers/how-weight-lose-zepbound-3575539/

Zepbound and Stomach Paralysis: Understanding the Connection

What is Stomach Paralysis?

First, let’s talk about stomach paralysis, also known as gastroparesis. It’s a condition where the stomach doesn’t empty food properly. When this happens, people can feel really full quickly, experience nausea, vomiting, and have a hard time managing their blood sugar and nutrition.

Possible Zepbound’s Role in stomach paralysis

Now, Zepbound, or tirzepatide, works by affecting certain hormones in your body to reduce hunger and help you eat less. It’s given through a weekly injection under the skin. But here’s the catch: one of the precautions with Zepbound is that it might not be safe for people with severe stomach problems, including gastroparesis.

Why the Caution with Zepbound?

The reason for this caution is that Zepbound affects how your stomach and intestines work. It can slow down how fast your stomach empties food. For someone with gastroparesis, this could make their symptoms worse. That’s why doctors are careful about prescribing Zepbound to people with this condition.

What You Should Do

If you’re considering Zepbound for weight loss, it’s super important to talk to your doctor about your entire health history, including any stomach issues. And if you’re already on Zepbound and start having stomach problems, you should definitely let your doctor know.

Remember, every medication has its benefits and risks, and it’s all about finding what’s safe and effective for you.

Source: https://www.health.harvard.edu/staying-healthy/questions-and-answers-about-the-new-anti-obesity-medications

In Summary

Zepbound can be a helpful tool for weight loss, but it needs to be used carefully, especially if you have stomach issues like gastroparesis. Always work closely with your healthcare provider to make sure any medication you take is safe and right for your specific health needs.

Zepbound Availability

Medrocs Pharmacy is proud to announce the complete availability of Zepbound, a groundbreaking weight loss medication, across all strengths in our inventory.

Understanding the urgent needs of our customers, we ensure availability of Zepbound, making it convenient for you to access this effective treatment same day. To make Zepbound more accessible, we accept the Zepbound coupon, significantly reducing the cost and making it an affordable option for those in need of chronic weight management solutions. 

Our commitment to quality and trust is demonstrated through our choice of suppliers; Zepbound is exclusively purchased from reputed suppliers in the USA, guaranteeing you receive only the highest quality medication.

Zepbound vs Mounjaro

FeaturesZepboundMounjaro
Generic NameTirzepatideTirzepatide (same as Zepbound)
IndicationsWeight management in adults with obesity or overweight with at least one weight-related conditionType 2 diabetes management, and also used off-label for weight loss
Mechanism of ActionGLP-1 and GIP receptor agonistGLP-1 and GIP receptor agonist (same as Zepbound)
AdministrationSubcutaneous injectionSubcutaneous injection (same as Zepbound)
Common Side EffectsNausea, diarrhea, decreased appetite, vomiting, constipation, abdominal painNausea, diarrhea, decreased appetite, vomiting, abdominal pain, constipation
Available StrengthsZepbound 2.5 mg Pen
Zepbound 5.0 mg Pen
Zepbound 7.5 mg Pen
Zepbound 10 mg Pen
Zepbound 12.5 mg Pen
Zepbound 15 mg Pen		Mounjaro 2.5 mg Pen
Mounjaro 5.0 mg Pen
Mounjaro 7.5 mg Pen
Mounjaro 10 mg Pen
Mounjaro 12.5 mg Pen
Mounjaro 15 mg Pen

Both Zepbound and Mounjaro share the same active ingredient (Tirzepatide) and mechanism of action. While Zepbound is primarily indicated for weight management in adults with obesity or overweight with weight-related conditions, Mounjaro is officially approved for the management of Type 2 diabetes but is also used off-label for weight loss. The administration method is the same for both drugs, and they share similar common side effects.

Common Zepbound related Questions and Answers.

Is Zepbound same as  Mounjaro?

Zepbound and Mounjaro both contain the active ingredient tirzepatide, indicating they are essentially the same medication in terms of their active component. However, the branding and specific indications for use may differ. Zepbound is primarily marketed for weight management in adults with obesity or overweight with at least one weight-related condition, emphasizing its role in weight loss and obesity treatment.

Mounjaro, on the other hand, is approved for the management of Type 2 diabetes. It’s worth noting that medications like these, which are effective in controlling blood sugar levels, often have the added benefit of promoting weight loss. This dual functionality makes tirzepatide a valuable treatment option for individuals with Type 2 diabetes who are also overweight or obese, and it’s likely that some healthcare providers may prescribe it off-label for weight loss alone.

The core similarity between Zepbound and Mounjaro lies in their mechanism of action, as both drugs function as GLP-1 and GIP receptor agonists. This means they work by enhancing the body’s natural production of insulin in response to elevated blood sugar levels while also suppressing appetite, which can lead to weight loss.

Zepbound and Alcohol (Can you drink on Zepbound?)

Generally Zepbound and Alcohol do not have any direct interactions but drinking Alcohol may affect the blood glucose levels indirectly. 

Both hypoglycemia(low blood sugar) & hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink. You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides,& neuropathy (nerve damage), or pancreatitis. Moderate alcohol consumption generally does not affect blood glucose levels if your diabetes is under control.

Alcohol may interfere with the mechanisms of weight loss drugs that aim to reduce appetite or increase satiety.

Is Zepbound covered by Insurance?

Yes, Zepbound is covered by many major insurance plans, which means you can get help with the cost of this weight loss medication. Some of the big insurance names that cover Zepbound include UnitedHealthcare, Blue Cross Blue Shield, Aetna, and Cigna. 

However, it’s always a good idea to check with your specific insurance provider to make sure Zepbound is covered under your plan. This way, you can be sure about the coverage details and any possible out-of-pocket costs you might have.

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